Effect of 1% Povidone Iodine Mouthwash/Gargle, Nasal and Eye Drop in COVID-19 patient

Authors

  • Md. Iqbal Mahmud Choudhury, Nilufar Shabnam, Tazin Ahsan, Md. Saiful kabir, Rashed Md. Khan and S.M. Abu Ahsan Plastic Surgery Unit, Department of Surgery, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka.

Keywords:

Povidone Iodine, 1Pq.s, COVID-19

Abstract

Background: The sudden onset of COVID-19 began in late 2019 caused by a novel coronavirus (SARS-COV2) and on 11th March, WHO declared it to have developed pandemic status. There is still no specific treatment and vaccine available for COVID-19; causing wide spread health problem and concern of the globe. Povidone iodine (PVP-I) is an antiseptic that has been used for over 150 years. It is already proved that different concentration of PVP-I can deactivate COVID-19 virus. Methodology: In this randomized controlled clinical trial, out of 1113 patients 606 patients were enrolled and divided in 2 groups by randomization after taken consents. In Gr-A, 303 patients underwent mouthwash/gargle, nasal drops and eye drops with 1% povidone iodine 4 hourly for 4 weeks as well as symptomatic treatment according to need. In Gr-B 303 patients were advised mouthwash/gargle, nasal cavity and eye wash with lukewarm water 4 hourly for 4 weeks and symptomatic treatment according to need. RT-PCR test done every 3rd, 5th and 7th day and Thyroid hormone level (TSH,T3, T4, FT4) at 4th week for follow up. Results: The group of patients used 1% PVP-I have shown tremendously reduced mortality, morbidity and hospital as well as financial burden in this covid situation. Conclusion: Administration of 1% PVP-I as mouthwash/gargle, nasal or eye drop is simple, rapid and cost effective in reduction of mortality and morbidity by COVID-19.

 

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Published

2021-01-01

How to Cite

Md. Iqbal Mahmud Choudhury, Nilufar Shabnam, Tazin Ahsan, Md. Saiful kabir, Rashed Md. Khan and S.M. Abu Ahsan (2021) “Effect of 1% Povidone Iodine Mouthwash/Gargle, Nasal and Eye Drop in COVID-19 patient”, Bioresearch Communications-(BRC). Dhaka, Bangladesh, 7(1), pp. 919-923. Available at: https://www.bioresearchcommunications.com/index.php/brc/article/view/176 (Accessed: 21September2021).

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Original Article