A study on screening of blood donors for seroprevalence of transfusion transmitted infections at Transfusion Medicine department of Armed Forces Institute of Pathology (AFIP), Dhaka
Keywords:TTI -Transfusion Transmitted Infections, ICT Immunochromatographic Test, ELISA- Enzyme-Linked Immune sorbent Assay, NAT-Nucleic Acid Amplification Testing
Safe blood transfusion (SBT) is a challenge in the arena of Transfusion Medicine. Each transfusion carries a risk of transmitting blood-borne pathogens. The present study was therefore aimed to elucidate the prevalence of transfusion transmitted infection (TTI) on routine screening of blood donors with their seroprevalence. A retrospective cross sectional study was done from June 2018 to December 2018 over 7875 donors at Transfusion Medicine Departme of AFIP, Dhaka Cantonment. Total 41 were found reactive in the screening assays. The prevalence of HBV, HCV and HIV in our study population was 0.4%, 0.03% and 0.03% respectively. Every ICT reactive sample were re-testified by ELISA to confirm these positive cases. In ELISA among 37 HBV ICT positive samples 35 remain reactive. There was no positive case of Malaria and Syphilis. The study also revealed that HBsAg, Anti-HCV and Anti-HIV positive cases were more prevalent among young donors.