Betulin-3-caffeate and Amyrin from the Stem Bark of Barringtonia acutangula (L)

Authors

  • Md. Enamul Haque Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka-1000, Bangladesh
  • Zimam Mahmud Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka-1000, Bangladesh
  • A. K. M. Mahbub Hasan Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka-1000, Bangladesh
  • Roman Sardar Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka-1000, Bangladesh
  • Md. Lutful Kabir Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka-1000, Bangladesh
  • Sheikh Tanzina Haque Department of Applied Chemistry and Chemical Engineering, University of Dhaka

Keywords:

Barringtonia acutangula, chromatography, betulin-3-caffeate, amyrin, 1H NMR

Abstract

Barringtonia acutangula (Indian Oak) is an important medicinal plant of Bangladesh and India for its phytochemical and prognostic biomarkers in stem. This plant was selected based on its medicinal properties including antiasthmatic, anticold, antimalerial, antidiarrehal, antiprotozoal, antidyesntry stimulating properties. The coarsely powdered stem bark of B. acutangula was extracted with CHCl3. The concentrated extract was then fractioned with flash column chromatography using petroleum ether, ethyl acetate and methanol. The column fractions were further fractionated with gel permeating chromatography. Extensive preparative thin layer chromatography resulted in the isolation of two compounds which were identified as betulin-3-caffeate and amyrin. The structures of these compounds were determined by 1H NMR spectroscopy. This is the first report of the isolation of these compounds from this plant stem bark.

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Published

29-07-2022

How to Cite

Haque, M. E., Mahmud, Z., Hasan, A. K. M. M., Sardar, R., Kabir, M. L., & Haque, S. T. (2022). Betulin-3-caffeate and Amyrin from the Stem Bark of Barringtonia acutangula (L). Bioresearch Communications - (BRC), 1(2), 121–123. Retrieved from https://www.bioresearchcommunications.com/index.php/brc/article/view/162

Issue

Vol. 1 No. 2 (2015)

Section

Short Communication

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